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Tokpela's Mist

How is it made?
Artesian water from high in the Hira Mountains in Shiga Prefecture, Japan is passed through the most technically advanced RO (reverse osmosis) membrane to produce"pure/sterile water"− virus and bacteria free. Tokpela's Mist™ is then created through a proprietary process where ultrapure hydrogen is fused into this"pure water". This sequence is patent pending, both for its process and equipment. Tokpela's Mist™ is manufactured by 8knot Co., Ltd. of Japan.


What does it contain?
Tokpela's Mist™ contains 1.4 ppm of pure hydrogen. The water is pH 5.8 with oxidative reductive potential (ORP) of -500 mV. This ORP provides its remarkable free radical/reactive oxygen species (ROS) quenching antioxidant properties.


How does it work?
Reactive oxygen species (ROS) are created naturally by mitochondria, polluted air, ionizing radiation, heavy metals and chemicals, as well as oxidized lipids accompanying body's metabolism. ROS generally includes super oxide radicals, hydroxyl radicals, singlet molecular oxygen (1O2), and hydrogen peroxides (H2O2).Broadly speaking, ROS includes nitric oxide (NO), peroxynitrite (ONOO-), radical lipids such as alkoxyradicals and peroxyradical lipids. Our body with antioxidant supplements system is able to neutralize these ROS with glutathione, SOD (superoxide dismutase), and antioxidant vitamins and repair damaged cells to some extent. Excess ROS and/or free radicals overwhelm typical antioxidant levels − contributing factors in aging, cancer, and hardening of arteries, heart attack, spasm, virus infection, lung disorder, intestinal disease, and life style related diseases such as diabetes, high blood pressure, and high cholesterol.

FIGURE 1

Hydrogen− particularly ionic as in Tokpela's Mist™ − is the safest and most effective antioxidant. Hydrogen in Tokpela's Mist™ selectively neutralizes hydroxide radicals without reacting against other ROS that have useful roles such as killing bacteria, immune function, cancer prevention, generation of blood vessels, and neural transmission. (Ohsawa, etal., 2007) Fig. 1 − after Bittner, etal., 2006. 2007 − illustrates hydrogen first activates and enhances the activities of ceruloplasm (an enzyme in the body), SOD, and intracellular GSH (reduced form of glutathione). Secondly, hydrogen also alters the surface electropotential of erythrocytes (red blood cells) which make them more flexible. It allows better circulation of blood particularly through the capillaries which are generally smaller than the cross-section of erythrocites. The combine effects of intake of hydrogen through Tokpela's Mist™ are the enhanced capacities in physical and cognitive performance. (Bittner, etal., 2007)


References
1. Bittner, A.C. & Sakuragi, Y. (2006), Intra-Individual Ergonomics (I2E): Framework and Future, Proc. 50th Annual Meeting Human Factors and Ergonomics Society (CD-ROM; pp. 2533-2537). Santa Monica, CA: HEFS.
2. Bittner, A.C.; Lile, Keith Jr.; Bittner, R.C. L; Sakuragi, Y (2007), Intra-Individual Ergonomics (I2E): Performance Effects of Ultra-Negative-Ion Water, Proc. 51st Annual Meeting Human Factors and Ergonomics Society (CD-ROM; pp. 1617-1621). Santa Monica, CA: HEFS.
3. Ohsawa, I., etal. (2007), Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals, Nature Medicine 13, 688-694.